Midnight Rider by The Allman Brothers Band is a great example of how we can connect the guitar lead part of a song with the chord strumming. The lead part is based around strings 5 and 4. Pay attention to your finger choices.
In this example, I prefer to play the 3rd fret on the 5th string with my second finger. As explained in the video lesson, by doing it that way, it will prepare you to play it together with the chord, but also it is somehow easier to play lines like this one with the 2nd finger.